NFL Week 13 Best Bets and Predictions

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nfl best bets

The best bets for NFL Week 13 include multiple Thanksgiving games, a special Black Friday game, and a dozen other exciting matchups. With all 32 teams taking the field this week, football fans have plenty of exciting wagers to choose from this weekend.

This guide will highlight the best NFL bets for Week 13, including the top points spreads and moneyline bets. I will tell you the best wagers available at top football betting sites and give my predictions.

Bovada Sportsbook provided the odds for my NFL best bets in Week 13.

Week 13 NFL Schedule

  • Chicago Bears vs. Detroit Lions (-10.0)
  • New York Giants vs. Dallas Cowboys (-3.5)
  • Miami Dolphins vs. Green Bay Packers (-3.0)
  • Las Vegas Raiders vs. Kansas City Chiefs (-12.0)
  • Los Angeles Chargers (-2.5) vs. Atlanta Falcons
  • Pittsburgh Steelers vs. Cincinnati Bengals (-3.0)
  • Houston Texans (-4.5) vs. Jacksonville Jaguars
  • Arizona Cardinals vs. Minnesota Vikings (-3.5)
  • Indianapolis Colts (-3.0) vs. New England Patriots
  • Seattle Seahawks (-2.0) vs. New York Jets
  • Tennessee Titans vs. Washington Commanders (-5.5)
  • Tampa Bay Buccaneers (-5.5) vs. Carolina Panthers
  • Los Angeles Rams (-3.0) vs. New Orleans Saints
  • Philadelphia Eagles vs. Baltimore Ravens (-3.0)
  • San Francisco 49ers vs. Buffalo Bills (-7.0)
  • Cleveland Browns vs. Denver Broncos (-5.5)

Best NFL Week 13 Point Spreads

Every NFL team is playing the week of Thanksgiving, so you have 16 exciting point spreads to choose from. Here are my NFL Week 13 best point spread bets.

Los Angeles Chargers vs. Atlanta Falcons (+2.5) (-115)

The Chargers fell short on Monday Night Football in Week 12, losing 30-23 to Baltimore. Atlanta was on a bye, but their 38-6 loss to Denver in Week 11 is still fresh in their minds. Both teams are desperate for a win, and I think the Falcons will step up at home.

Los Angeles is a 2.5-point road favorite in Atlanta this weekend. However, the Chargers run defense was exposed on MNF, and Atlanta can exploit similar weaknesses in the LA’s scheme.

The Falcons offense has failed to meet expectations, but their bye came at the right time. With two weeks to prepare, Atlanta is in an excellent position to cover the spread as a home underdog this week. They could win this game outright, so betting them at +2.5 is a good value.

Arizona Cardinals vs. Minnesota Vikings (-3.5) (-105)

Arizona is another team looking to bounce back from a tough loss in Week 12. The Cardinals lost 16-6 in Seattle, which cost Arizona the top spot in the NFC West. Arizona faces another challenging matchup this week on the road in Minnesota.

The Vikings (9-2) are 3.5-point home favorites against Arizona this weekend. Minnesota’s defense has generated 38 sacks this season, the fourth-most in the NFL. The Vikings also lead the league in interceptions with 16.

Arizona’s running game is the strength of its offense, and Minnesota is well-suited to stuff the Cardinals’ rushing attack. The Vikings allow the second-fewest rush yards per attempt (3.6) and have only allowed five rushing touchdowns. Minnesota wins and covers the 3.5-point spread at home this week.

Pittsburgh Steelers (+3.0) vs. Cincinnati Bengals (-115)

Pittsburgh’s loss to Cleveland last week jeopardized its slim lead in the AFC North. The Steelers can get revenge against the state of Ohio this week by beating the Bengals in Cincinnati. Secure sportsbooks list the Steelers as 3.0-point road underdogs this weekend.

The Bengals offense, led by Joe Burrow, has been one of the most efficient units in the league. However, the Bengals are 4-7 and winless against teams with a winning record. Cincinnati’s struggling defense will cost them again this weekend.

Russell Wilson’s play has declined with each start, and the sightings of Mr. Unlimited have increased every week. I think Mike Tomlin will reign in Wilson this week, and the Steelers will pull off the upset on the road in Cincinnati.

San Francisco 49ers vs. Buffalo Bills (-7.0) (-105)

When the schedule was released, this Week 13 matchup between the 49ers and the Bills was considered a potential Super Bowl 59 preview. The Bills (9-2) have held up their end of the deal. San Francisco, on the other hand, is 5-6 and could miss the playoffs this season.

Buffalo is a 7.0-point favorite at home against the 49ers on Sunday Night Football this week. If the 49ers’ tackling struggles continue, the Bills’ rushing attack could have its best game of the season against San Fran. The 49ers missed 19 tackles in their 38-10 loss to the Packers last week.

The historically bad loss was one of the worst of the Kyle Shanahan era. San Francisco could suffer an even worse loss this week if they cannot tackle Josh Allen, James Cook, and Amari Cooper. Buffalo will win and easily cover the touchdown spread this week.

NFL Week 13 Moneylines and Underdogs

Bovada Sportsbook also offers outstanding moneyline wagers for the top games this week. Here are my Week 13 NFL best moneyline bets.

Seattle Seahawks (-130) vs. New York Jets

One of my favorite teams to bet as an outright winner this week is the Seattle Seahawks. Seattle claimed the top spot in the NFC West with its 16-6 win over the Cardinals. The Seahawks’ lead in the division is slim, so they need to keep the momentum going this week.

The good news for Seattle fans is that they play the New York Jets. New York had a bye last week, so they should be well-rested for this matchup. Despite the rest, there is little to no reason to expect the Jets to win this game.

Aaron Rodgers has failed to defy Father Time this season, and the Jets, who are 3-8, have little other than pride to play for this week. Seattle is more motivated and, frankly, the better team in this matchup. The Seahawks will win this game and move one step closer to winning the NFC West.

Houston Texans (-225) vs. Jacksonville Jaguars

The AFC South has been even worse than expected this season. Houston currently leads the division at 7-5, but they have also lost three of their last four games. Not to be outdone, the Jaguars (2-9) have lost four straight ahead of this divisional matchup.

Houston’s slump has cost them any chance at securing a bye this postseason. However, the Texans can still secure a home playoff game by winning the division. Jacksonville could be the perfect opponent for a Texans team that needs to get back on track.

C.J. Stroud has struggled in his sophomore season, but Jacksonville’s defense is one of the worst units in the NFL. Jacksonville has allowed the second-most passing yards (3,192) and second-most passing touchdowns (23) this season. Stroud and company will bounce back this week and secure the divisional win. 

Tennessee Titans vs. Washington Commanders (-245)

Speaking of disappointing AFC South teams, the Will Levis-led Titans upset Houston last week to improve to 3-8. Tennessee faces another tough but flailing team this week: Washington (7-5). The Commanders have lost three straight games, and injuries are racking up on the offensive side of the ball.

Washington was in line to win the NFC East before its losing streak, and now it is in danger of missing the playoffs. Despite their injuries, Jayden Daniels and the Commanders will get back in the win column this weekend against the Titans.

The Titans’ offense did everything it could to lose last week, but the Texans were somehow worse. Washington has plenty of issues to work through, but I think they will make fewer mistakes than the Titans this week and win the game.

Philadelphia Eagles (+145) vs. Baltimore Ravens

Rounding out my list of the best NFL Week 13 bets are the Philadelphia Eagles. Philly is a +145 underdog this weekend against the Ravens in Baltimore. The Eagles (9-2) and the Ravens (8-4) are two of the top teams in the NFL, and this game will have significant playoff implications.

Philadelphia is the better team, and I think they will secure the upset in Baltimore. The Ravens have one of the worst passing defenses in the league, so A.J. Brown and DeVonta Smith should have a field day on Sunday.

Even if the Ravens stop the Eagles’ passing attack, they have no answer for Saquon Barkley. Philadelphia has too many weapons on offense for Baltimore to handle, and the Eagles will pull off the upset this week.

What Are Your Best NFL Week 13 Bets?

The best bets for NFL Week 13 offer dozens of exciting betting opportunities. Check out the guide above to see my top eight wagers for this week’s games.

After reading my predictions, create your Bovada account to wager on the best NFL bets for Week 13. If it is your first time betting at this site, you can use the code BV1000 to claim up to $1,000 for your Week 13 wagers.

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About the Author

Shaun Stack is a senior writer at GamblingSites.org. His gambling articles have appeared in the Daily Herald, Space Coast Daily, and NJ 101.5. He’s a football betting expert, a Survivor fan, and a skilled blackjack gambler. Shaun is a native of Kansas City but now lives in Pennsylvania and follows the Pittsburgh Steelers religiously.